InVivoSIM anti-human amyloid-beta (Lecanemab Biosimilar)
货号 #SIM0032
克隆号:
Lecanemab
反应种属:
Human
¥2,336 - ¥80,624
产品详情
This non-therapeutic biosimilar antibody uses the same variable regions from the therapeutic antibody Lecanemab making it ideal for research use. This Lecanemab biosimilar is a recombinant humanized IgG1 antibody directed against aggregated soluble and insoluble forms of amyloid-beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain with high selectivity to Aβ protofibrils.参数
同种型 | Human IgG1, κ |
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推荐的同型对照 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
推荐稀释缓冲液 | InVivoPure pH 7.0 Dilution Buffer |
免疫原 | Human amyloid-beta |
Reported Applications | Functional assays |
形式 | PBS, pH 7.0 Contains no stabilizers or preservatives |
内毒素 | <1EU/mg (<0.001EU/μg) Determined by LAL gel clotting assay |
聚合 | <5% Determined by SEC |
纯化 | >95% Determined by SDS-PAGE |
无菌性 | 0.2 μM filtration |
生产 | Purified from cell culture supernatant |
提纯 | Protein A |
分子量 | 150 kDa |
小鼠病原体试验 | Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Minute Virus: Negative Mouse Hepatitis Virus: Negative Reovirus Screen: Negative Lymphocytic Choriomeningitis virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Mouse Rotavirus: Negative Theiler's Murine Encephalomyelitis: Negative Ectromelia/Mousepox Virus: Negative Hantavirus: Negative Polyoma Virus: Negative Mouse Adenovirus: Negative Sendai Virus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Mouse Cytomegalovirus: Negative K Virus: Negative |
保存 | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |