生物仿制抗体
What Are InVivoSIM™ Biosimilar Antibodies?
Bio X Cell InVivoSIM™ Biosimilar Antibodies are research-grade biosimilar monoclonal antibodies. Each biosimilar antibody is produced using recombinant technology and incorporates the same variable region sequence as the original pharmaceutical drug.
Biosimilar antibodies make it possible to study the biological effects of a drug without needing to source expensive pharmaceutical-grade therapeutics. They can be used for many research applications including functional assays, flow cytometry, ELISA, Immunohistochemistry, pharmacokinetic assays, and others.
InVivoSIM™ biosimilar antibodies are offered with the same purity and in vivo formulations that Bio X Cell is known for. Our biosimilar antibodies are of exceptional quality and consistency. They are ultra-pure and free of preservatives, stabilizers, and carrier proteins, making them ideal for in vivo applications including drug efficacy studies in humanized mouse models.
InVivoSIM™ Biosimilar Antibodies Feature
- Exceptional Purity Each lot is QC tested for purity using SDS-PAGE and are preservative, stabilizer, and carrier protein-free.
- Binding Validation Each lot of InVivoSIM™ product is validated for antigen binding by immunoblot.
- Ultra-low Endotoxin Levels The level of endotoxin is QC tested for each lot. Our InVivoSIM™ biosimilar antibodies are ≤ 1EU/mg. If endotoxin levels below 1EU/mg are required, please contact technical support to discuss your needs.
- Pathogen Free Each lot of InVivoSIM™ product is screened for an exhaustive panel of murine pathogens. The results are detailed on product-specific datasheets, to help you adhere to IACUC and Animal Facility requirements.
- Low Protein Aggregation Each lot of InVivoSIM™ product is QC tested for aggregate level and guaranteed to be below 5% of the total protein.
InVivoSIM™ Biosimilar Antibodies are for Research Use Only (RUO) and Not For Therapeutic Use.
| InVivoSIM anti-human TNFα (Adalimumab Biosimilar) | Human | Human IgG1 | SIM0001 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human EGFR (Cetuximab Biosimilar) | Human | Human IgG1 | SIM0002 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human PD-1 (Nivolumab Biosimilar) | Human | Human IgG4 | SIM0003 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human CTLA-4 (Ipilimumab Biosimilar) | Human | Human IgG1 | SIM0004 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human HER2 (Trastuzumab Biosimilar) | Human | Human IgG1 | SIM0005 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human TNFα (Infliximab Biosimilar) | Human | Human IgG1 | SIM0006 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human VEGF (Bevacizumab Biosimilar) | Human | Human IgG1 | SIM0007 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human CD20 (Rituximab Biosimilar) | Human | Human IgG1 | SIM0008 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human PD-L1 (Atezolizumab Biosimilar) | Human | Human IgG1 | SIM0009 | RecombiMAb human IgG1 (N297A) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human PD-1 (Pembrolizumab Biosimilar) | Human | Human IgG4 | SIM0010 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human C5 (Eculizumab Biosimilar) | Human | Human IgG4 | SIM0011 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human VEGFR-2 (Ramucirumab Biosimilar) | Human | Human IgG1 | SIM0012 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-17A (Secukinumab Biosimilar) | Human | Human IgG1 | SIM0013 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-6R (Tocilizumab Biosimilar) | Human | Human IgG1 | SIM0014 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human LAG-3 (Relatlimab Biosimilar) | Human | Human IgG4, κ | SIM0015 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IgE (Omalizumab Biosimilar) | Human | Human IgG1, κ | SIM0016 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human NGF (Tanezumab Biosimilar) | Human | Human IgG2, κ | SIM0017 | InVivoPlus human IgG2 isotype control |
| InVivoSIM anti-human integrin α4β1 (VLA-4) | Human IgG4, κ | SIM0018 | InVivoMAb polyclonal human IgG | |
| InVivoSIM anti-human HER2 (Pertuzumab Biosimilar) | Human IgG1, κ | SIM0019 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme | |
| InVivoSIM anti-human IL-12 p40 (Ustekinumab Biosimilar) | Human | Human IgG1, κ | SIM0020 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human PD-L1 (Avelumab Biosimilar) | Human | Human IgG1, λ | SIM0021 | RecombiMAb human IgG1 isotype control, anti-respiratory syncytial virus |
| InVivoSIM anti-human IFNAR1 (Anifrolumab Biosimilar) | Human | Human IgG1, κ | SIM0022 | RecombiMAb human IgG1 (K214R/L234F/L235E/P331S) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-4Rα (CD124) (Dupilumab Biosimilar) | Human | Human IgG4, κ | SIM0023 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human integrin α4β7 (LPAM-1) (Vedolizumab Biosimilar) | Human | Human IgG1, κ | SIM0024 | RecombiMAb human IgG1 (LALA-PG) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-23 (p19) (Guselkumab Biosimilar) | Human | Human IgG1, λ | SIM0025 | RecombiMAb human IgG1 isotype control, anti-respiratory syncytial virus |
| InVivoSIM anti-human Claudin 18.2 (Zolbetuximab Biosimilar) | Human | Human IgG1, κ | SIM0026 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human PD-L1 (Durvalumab Biosimilar) | Human | Human IgG1, κ | SIM0027 | RecombiMAb human IgG1 (LALA-PG) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human RANKL (CD254) (Denosumab Biosimilar) | Human | Human IgG1, κ | SIM0028 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-17A (Ixekizumab Biosimilar) | Human | Human IgG4, κ | SIM0029 | RecombiMAb human IgG4 (S228P) isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human IL-6 (Siltuximab Biosimilar) | Human | Human IgG1, κ | SIM0030 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human nectin-4 (Enfortumab Biosimilar) | Human | Human IgG1, κ | SIM0031 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
| InVivoSIM anti-human amyloid-beta (Lecanemab Biosimilar) | Human | Human IgG1, κ | SIM0032 | RecombiMAb human IgG1 isotype control, anti-hen egg lysozyme |
