InVivoMAb anti-mouse IL-12 p40

货号 #BE0051
克隆号:
C17.8
反应种属:
Mouse

¥1,712 - ¥44,512

选择参数
  • 100 mg - ¥44,512
  • 50 mg - ¥31,456
  • 25 mg - ¥20,896
  • 5 mg - ¥6,240
  • 1 mg - ¥1,712
  • 定制包装(请询价)

产品详情

The C17.8 antibody reacts with mouse p40 also known as IL-12β. p40 is a 40 kDa subunit of IL-12 and IL-23. IL-12 is a heterodimeric cytokine composed of subunits IL-12α p35 and IL-12β p40. The p40 subunit of IL-12 also combines with p19, a protein that shows no biological activity by itself, to form IL-23. IL-12 is secreted by activated monocytes, macrophages, and dendritic cells while IL-23 is secreted by activated dendritic cells and epithelial cells. IL-12 plays roles in T lymphocyte differentiation, IFNγ production, and NK cell cytotoxicity. The C17.8 antibody has been shown to neutralize both IL-12 and IL-23 bioactivity.

参数

同种型 Rat IgG2a, κ
推荐的同型对照 InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
推荐稀释缓冲液 InVivoPure pH 7.0 Dilution Buffer
免疫原 Recombinant mouse IL-12 p70
Reported Applications in vivo IL-12p40 neutralization p40 affinity chromatography Immunoprecipitation ELISA Flow cytometry Western blot
形式 PBS, pH 7.0 Contains no stabilizers or preservatives
内毒素 <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
纯化 >95% Determined by SDS-PAGE
无菌性 0.2 μM filtration
生产 Purified from tissue culture supernatant in an animal free facility
提纯 Protein G
RRID AB_1107698
分子量 150 kDa
保存 The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

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