InVivoMAb anti-mouse IL-6

货号 #BE0046
克隆号:
MP5-20F3
反应种属:
Mouse

¥1,712 - ¥44,512

选择参数
  • 100 mg - ¥44,512
  • 50 mg - ¥31,456
  • 25 mg - ¥20,896
  • 5 mg - ¥6,240
  • 1 mg - ¥1,712
  • 定制包装(请询价)

产品详情

The MP5-20F3 monoclonal antibody reacts with mouse IL-6 (interleukin-6) a 21-28 kDa cytokine that is expressed by many cell types, including T lymphocytes, B lymphocytes, monocytes, fibroblasts, and endothelial cells. IL-6 signals through a cell-surface type I cytokine receptor complex consisting of the ligand-binding IL-6Rα chain (CD126), and the signal-transducing component gp130 (also called CD130). Upon receptor binding IL-6 influences antigen-specific immune responses, inflammatory responses, neuronal development, and is a major mediator of the acute phase reaction. The MP5-20F3 monoclonal antibody has been shown to neutralize the bioactivity of natural or recombinant IL-6.

参数

同种型 Rat IgG1, κ
推荐的同型对照 InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase
推荐稀释缓冲液 InVivoPure pH 7.0 Dilution Buffer
免疫原 Recombinant mouse IL-6
Reported Applications in vivo IL-6 neutralization in vitro IL-6 neutralization
形式 PBS, pH 7.0 Contains no stabilizers or preservatives
内毒素 <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
纯化 >95% Determined by SDS-PAGE
无菌性 0.2 μM filtered
生产 Purified from tissue culture supernatant in an animal free facility
提纯 Protein G
RRID AB_1107709
分子量 150 kDa
保存 The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
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