InVivoPlus anti-mouse IL-17A

货号 #BP0173
克隆号:
17F3
反应种属:
Mouse

¥8,128 - ¥57,904

选择参数
  • 100 mg - ¥57,904
  • 50 mg - ¥40,928
  • 25 mg - ¥27,200
  • 5 mg - ¥8,128
  • 定制包装(请询价)

产品详情

The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-17A in vivo.

参数

同种型 Mouse IgG1, κ
推荐的同型对照 InVivoPlus mouse IgG1 isotype control, unknown specificity
推荐稀释缓冲液 InVivoPure pH 7.0 Dilution Buffer
免疫原 Mouse IL-17A cross-linked to OVA
Reported Applications in vivo IL-17A neutralization
形式 PBS, pH 7.0 Contains no stabilizers or preservatives
内毒素* <1EU/mg (<0.001EU/μg) Determined by LAL gel clotting assay
聚合* <5% Determined by SEC
纯化 >95% Determined by SDS-PAGE
无菌性 0.2 μM filtration
生产 Purified from tissue culture supernatant in an animal free facility
提纯 Protein G
RRID AB_10950102
分子量 150 kDa
小鼠病原体试验* Mouse Norovirus: Negative Mouse Parvovirus: Negative Mouse Minute Virus: Negative Mouse Hepatitis Virus: Negative Reovirus Screen: Negative Lymphocytic Choriomeningitis virus: Negative Lactate Dehydrogenase-Elevating Virus: Negative Mouse Rotavirus: Negative Theiler's Murine Encephalomyelitis: Negative Ectromelia/Mousepox Virus: Negative Hantavirus: Negative Polyoma Virus: Negative Mouse Adenovirus: Negative Sendai Virus: Negative Mycoplasma Pulmonis: Negative Pneumonia Virus of Mice: Negative Mouse Cytomegalovirus: Negative K Virus: Negative
保存 The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

其他系列同指标产品

点击关闭